Wednesday, 28th of May 2008

This program is permanently updated according to the answers of the solicited speakers.

Sessions of the day : Heart, laminopathies and dystrophinopathies 

morning Session : heart

8h30
9h15
Plenary lectureplenary lecture (auditorium)

“How to make a heart : mulitpotent cardiovascular progenitors in development and disease”


Lecturer : Kenneth Chien, USA

Chairpersons : Pascale Guicheney and Claude Desnuelle
9h15
10h00
Plenary lectureplenary lecture (auditorium)

“Perindopril treatment in Duchenne Muscular Dystrophy and prevention of sudden death in Laminopathies”


Lecturer : Denis Duboc, France

Chairpersons : Pascale Guicheney and Claude Desnuelle
10h00
10h30
BreakBreak
10h30
12h00
Parallel symposiaparallel symposia
 
“Fundamental aspects of heart development” (Amphithéâtre Callelongue)


Chairpersons : Joël Nargeot and Jean Jacques Schott

Michel Pucéat (France) : Cardiac commitment of human embryonic stems cells : towards the generation of cardiac progenitors for cell therapy of heart failure


Bernard K. Fleischmann (Germany) : The potential and pitfalls of cell replacement strategies in the heart

Robert G. Kelly (France) : Myocardial progenitor cells in early embryo
 
 
“Cardiomyopathies and experimental models” (Salle Endoume)


Chairpersons : Denise Paulin and Urs Ruegg

Gisèle Bonne (France) : Animal models in laminopathies

Angelo Parini (France) : Animal models of cardiac cell therapy : how and why


Christelle Monville (France) : An in vitro beating heart model for functional assessment of pharmacological compounds and cell therapy
 
“Cell or pharmacotherapy of cardiomyopathy” (Auditorium)


Chairpersons : Yves Fromes and Michel Villaz

Patricia Le Marchand (France) : Cardiac cell therapy : clinical trials


Jean-Thomas Vilquin (France) : Myoblast transplantation in heart failure : the MAGIC study

Christine Mummery (The Netherlands) : Cardiomyocytes from human embryonic stem cells and cardiac regeneration
12h00 13h00
Lunchlunch break

13h00 14h30
BreakPoster walk (salle les goudes

afternoon sessions : laminopathies and dystrophinopathies

14h30 15h15
Plenary lectureplenary lecture (auditorium)

“Laminopathies in human and mouse : from gene defects to therapies”


Lecturer : Nicolas Lévy, France

Chairpersons : Georges Serratrice and Carlo Minetti
15h15 16h00
Plenary lectureplenary lecture (auditorium)

"Treat-NMD and
transnational research"


Lecturer : Kate Bushby, UK

Chairpersons : Georges Serratrice and Carlo Minetti
16h00 16h30
Breakbreak
16h30
17h30
Parallel symposiaparallel symposia
 
"New insight in laminopathies" (Amphithéâtre Callelongue)


Chairpersons : Gisèle Bonne and John Vissing

Howard J. Worman (canada) : MAP Kinase signalling and cardiomyopathy in Emery-Dreifuss muscular dystrophy


Chris Hutchison (UK) : Novel functions of emerin in cytoskeleton organisation and gene regulation

Roland Foisner (Austria) : Nucleoplasmic lamin complexes regulate muscle progenitor cells
 
"New approaches to the therapy of dystrophinopathies" (Auditorium)


Chairpersons : Mireille Claustres and Jean-Claude Kaplan

Yvan Torrente (Italy) : Autologous transplantation of engineered muscle-derived CD133+ stem cells


Jamel Chelly (France) : Molecular diagnosis and ex-vivo validation of therapeutic approaches in dystrophinopathies

Isabelle Richard (France) : Mannosidase I inhibition rescues the human alpha-sarcoglycan R77C recurrent mutation 
 
"Innovativ approaches to therapy" (salle Endoume)


Chairpersons : François Rivier et Philippe Gailly

Vincenzo Nigro (Italy) : Systemic delta-sarcoglycan gene delevery avoids life long evolution of cardiomyopathy and muscular dystrophy of Bio 14.6 hamster

Alessandra Ferlini (Italy) : The systemic administration of a low dose of 20M2ePS-AON combinated with novel cationic polymethyl mathacrylate nanoparticles induce the rescue of dystrophin expression in both cardiac and skeletal muscle in mdx murine model

Philippe Moullier (France) : Adeno-associated viral vector genomes persist as episomal chromatin in primate skeletal muscle
17h30 18h30
Plenary lectureplenary lecture (auditorium)

“Splice intervention therapies for muscle diseases”


Lecturer : Steve Wilton, Australia

Chairperson : Thomas Sejersen
19h00 20h00
Symposia parallèlessatellite Symposium organized by genzyme (amphithéâtre callelongue)
“New insights in Pompe disease”


Chairpersons : Brigitte Chabrol and Jean Pouget

Lecturers :

19h00 – 19h40 :  Pascal Laforêt, France
Clinical experience of Myozyme®

19h40 – 20h00 :  David Orlikowski, France
The point of view of the pulmonologist